Observation of Bothrops atrox Snake Envenoming Blister Formation from Five Patients: Pathophysiological Insights

In the Brazilian Amazon, Bothrops atrox snakebites are frequent, and patients develop tissue damage with blisters sometimes observed in the proximity of the wound. Antivenoms do not seem to impact blister formation, raising questions regarding the mechanisms underlying blister formation. Here, we la...

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Veröffentlicht in:	Toxins 2021-11, Vol.13 (11), p.800, Article 800
Hauptverfasser:	Gimenes, Sarah N. C., Sachett, Jacqueline A. G., Colombini, Monica, Freitas-de-Sousa, Luciana A., Ibiapina, Hiochelson N. S., Costa, Allyson G., Santana, Monique F., Park, Jeong-Jin, Sherman, Nicholas E., Ferreira, Luiz C. L., Wen, Fan H., Monteiro, Wuelton M., Moura-da-Silva, Ana M., Fox, Jay W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-inflammatory agents Antivenins - administration & dosage Antivenins - metabolism Antivenom blister Blister - metabolism Blistering Blisters Bothrops Bothrops atrox Brazil Crotalid Venoms - antagonists & inhibitors Crotalid Venoms - toxicity Damage patterns DAMPs Edema Female Food Science & Technology Gelatinase B Hospitalization Hospitals Humans Immunomodulation Immunomodulators Inflammation Laboratories Life Sciences & Biomedicine local damage Male Matrix metalloproteinase Matrix metalloproteinases Metalloproteinase Pain Pathophysiology Patients Proteins Proteomics Science & Technology Snake bites Snake Bites - complications Snake Bites - therapy snake venom Toxicology Toxins Venom
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