An Immunohistochemical Evaluation of Tumor-Associated Glycans and Mucins as Targets for Molecular Imaging of Pancreatic Ductal Adenocarcinoma

Targeted molecular imaging may overcome current challenges in the preoperative and intraoperative delineation of pancreatic ductal adenocarcinoma (PDAC). Tumor-associated glycans Lea/c/x, sdi-Lea, sLea, sLex, sTn as well as mucin-1 (MUC1) and mucin-5AC (MU5AC) have gained significant interest as tar...

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Veröffentlicht in:	Cancers 2021-11, Vol.13 (22), p.5777
Hauptverfasser:	Houvast, Ruben D., Thijse, Kira, Groen, Jesse V., Chua, JiaXin, Vankemmelbeke, Mireille, Durrant, Lindy G., Mieog, J. Sven D., Bonsing, Bert A., Vahrmeijer, Alexander L., Kuppen, Peter J. K., Crobach, A. Stijn L. P., Sier, Cornelis F. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Automation Biobanks Biomarkers Disease Duodenum Image processing Immunohistochemistry Lymph nodes Lymphatic system Metastases Metastasis Mucin Pancreatic cancer Pancreatitis Patients Polysaccharides Proteins Small intestine Statistical analysis Surgery Tracers Tumor cells
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