Cytokine-scavenging nanodecoys reconstruct osteoclast/osteoblast balance toward the treatment of postmenopausal osteoporosis

Imbalance between osteoblasts and osteoclasts accounts for the incidence and deterioration of postmenopausal osteoporosis. Abnormally elevated RANKL and TNF-α levels after menopause promote osteoclast formation and inhibit osteoblast differentiation, respectively. Here, nanodecoys capable of scaveng...

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Veröffentlicht in:Science advances 2021-11, Vol.7 (48), p.eabl6432-eabl6432
Hauptverfasser: Zhou, Yang, Deng, Yekun, Liu, Zhongmin, Yin, Mengyuan, Hou, Mengying, Zhao, Ziyin, Zhou, Xiaozhong, Yin, Lichen
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Sprache:eng
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