Idiopathic early ovarian aging: is there a relation with premenopausal accelerated biological aging in young women with diminished response to ART?

Purpose To evaluate whether young women with idiopathic early ovarian aging, as defined by producing fewer oocytes than expected for a given age over multiple in vitro fertilization (IVF) cycles, have changes in telomere length and epigenetic age indicating accelerated biological aging (i.e., increa...

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Veröffentlicht in:	Journal of assisted reproduction and genetics 2021-11, Vol.38 (11), p.3027-3038
Hauptverfasser:	Christensen, Mette W., Keefe, David L., Wang, Fang, Hansen, Christine S., Chamani, Isaac J., Sommer, Carolyn, Nyegaard, Mette, Rohde, Palle D., Nielsen, Anders L., Bybjerg-Grauholm, Jonas, Kesmodel, Ulrik S., Knudsen, Ulla B., Kirkegaard, Kirstine, Ingerslev, Hans Jakob
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aging Anti-Mullerian Hormone - blood Biomarkers Case-Control Studies DNA Methylation Epigenetics Female Fertility Fertilization in Vitro Follicle Stimulating Hormone - blood Follicle-stimulating hormone Gynecology Human Genetics Humans In vitro fertilization Leukocytes Medicine Medicine & Public Health Morbidity Oocytes Oocytes - pathology Ovarian Diseases - pathology Ovarian Follicle - pathology Ovarian Reserve Ovaries Pregnancy Pregnancy Rate Premenopause Prospective Studies Reproductive Medicine Reproductive Physiology and Disease Reproductive status Sperm Injections, Intracytoplasmic Telomere Homeostasis Telomeres
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