An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice

The purpose of this study was to present our hypothesis that aging alters metabolic function in ocular tissues. We tested the hypothesis by measuring metabolism in aged murine tissues alongside retinal responses to light. Scotopic and photopic electroretinogram (ERG) responses in young (3-6 months)...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2021-11, Vol.62 (14), p.20-20
Hauptverfasser:	Tsantilas, Kristine A, Cleghorn, Whitney M, Bisbach, Celia M, Whitson, Jeremy A, Hass, Daniel T, Robbings, Brian M, Sadilek, Martin, Linton, Jonathan D, Rountree, Austin M, Valencia, Ana P, Sweetwyne, Mariya T, Campbell, Matthew D, Zhang, Huiliang, Jankowski, Connor S R, Sweet, Ian R, Marcinek, David J, Rabinovitch, Peter S, Hurley, James B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Aging - physiology Animals Biochemistry and Molecular Biology Color Vision - physiology Electroretinography Flicker Fusion - physiology Gas Chromatography-Mass Spectrometry Glucose - metabolism Glutamine - metabolism Light Male Metabolomics Mice Mice, Inbred C57BL Night Vision - physiology Oxygen Consumption - physiology Photic Stimulation Retina - metabolism Retinal Pigment Epithelium - metabolism
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