The Effects of Freshwater Clam (Corbicula fluminea) Extract on Activated Hepatic Stellate Cells

Background. The extract of freshwater clams has been used to protect the body against liver diseases in traditional folk medicine. This study aims at investigating the effects of freshwater clam extract on activated hepatic stellate cells (aHSCs), which are critical contributors to liver fibrosis. M...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2021, Vol.2021, p.6065168-10
Hauptverfasser:	Lee, Shou-Lun, Hsu, Wei-Hsiang, Tu, Chia-Ming, Wang, Wen-Han, Yang, Cheng-Yao, Lee, Hsien-Kuang, Chin, Ting-Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture Cell cycle Cell growth Collagen (type I) Cyclin D1 Cytokines Deactivation Extracellular matrix Fibrosis Flow cytometry Gelatinase B Liver cirrhosis Liver diseases Mollusks Peroxisome proliferator-activated receptors Phenotypes Phenotypic plasticity Polymerase chain reaction Proteins Stellate cells Tumor necrosis factor-α
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