A highly annotated database of genes associated with platinum resistance in cancer

Platinum-based chemotherapy, including cisplatin, carboplatin, and oxaliplatin, is prescribed to 10-20% of all cancer patients. Unfortunately, platinum resistance develops in a significant number of patients and is a determinant of clinical outcome. Extensive research has been conducted to understan...

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Veröffentlicht in:	Oncogene 2021-11, Vol.40 (46), p.6395-6405
Hauptverfasser:	Huang, Dongqing, Savage, Sara R., Calinawan, Anna P., Lin, Chenwei, Zhang, Bing, Wang, Pei, Starr, Timothy K., Birrer, Michael J., Paulovich, Amanda G.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1517/1709 692/53/2423 Apoptosis Cancer Cancer research Carboplatin Cell Biology Cell survival Chemotherapy Cisplatin Data Curation Databases, Genetic Detoxification DNA damage Drug resistance Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic Gene Regulatory Networks Genetic aspects Human Genetics Humans Internal Medicine Medical research Medicine Medicine & Public Health Neoplasms - drug therapy Neoplasms - genetics Oncology Oncology, Experimental Online databases Oxaliplatin Patient outcomes Patients Platinum Platinum - pharmacology Platinum - therapeutic use Review Review Article Tumor microenvironment Tumor Microenvironment - drug effects Tumors
Online-Zugang:	Volltext
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