HIV Transgenic Rats Demonstrate Impaired Sensorimotor Gating But Are Insensitive to Cannabinoid (Δ9-Tetrahydrocannabinol)-Induced Deficits

Abstract Background HIV-associated neurocognitive disorder (HAND) is commonly observed in persons living with HIV (PWH) and is characterized by cognitive deficits implicating disruptions of fronto-striatal neurocircuitry. Such circuitry is also susceptible to alteration by cannabis and other drugs o...

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Veröffentlicht in:	The international journal of neuropsychopharmacology 2021-11, Vol.24 (11), p.894-906
Hauptverfasser:	Roberts, Benjamin Z, Minassian, Arpi, Halberstadt, Adam L, He, Yinong V, Chatha, Muhammad, Geyer, Mark A, Grant, Igor, Young, Jared W
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Animals Cannabidiol - pharmacology Cannabinoid Receptor Agonists - pharmacology Cannabinoids Cannabinoids - pharmacology Care and treatment Cognition disorders Complications and side effects Demographic aspects Dronabinol - pharmacology Female Hallucinogens - pharmacology Health aspects HIV infection HIV Infections - physiopathology Male Prepulse Inhibition - drug effects Rats Rats, Transgenic Reflex, Startle - drug effects Regular s Risk factors Sensory Gating - drug effects
Online-Zugang:	Volltext
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