Volumetric interferometric lattice light-sheet imaging

Live cell imaging with high spatiotemporal resolution and high detection sensitivity facilitates the study of the dynamics of cellular structure and function. However, extracting high-resolution 4D (3D space plus time) information from live cells remains challenging, because current methods are slow...

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Veröffentlicht in:	Nature biotechnology 2021-11, Vol.39 (11), p.1385-1393
Hauptverfasser:	Cao, Bin, Coelho, Simao, Li, Jieru, Wang, Guanshi, Pertsinidis, Alexandros
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/245/2225 631/57/2265 Agriculture Bioinformatics Biological activity Biological analysis Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Cellular structure Cytoskeleton Dynamic structural analysis Excitation Imaging Imaging systems Imaging, Three-Dimensional - methods Interferometry Life Sciences Light Light levels Light sheets Localization Methods Microscopy Microscopy, Fluorescence - methods Mitochondria mRNA Organelles Signal processing Signal to noise ratio Structure-function relationships Transcription
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