How Tim proteins differentially exploit membrane features to attain robust target sensitivity

Immune surveillance cells such as T cells and phagocytes utilize integral plasma membrane receptors to recognize surface signatures on triggered and activated cells such as those in apoptosis. One such family of plasma membrane sensors, the transmembrane immunoglobulin and mucin domain (Tim) protein...

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Veröffentlicht in:	Biophysical journal 2021-11, Vol.120 (21), p.4891-4902
Hauptverfasser:	Kerr, Daniel, Gong, Zhiliang, Suwatthee, Tiffany, Luoma, Adrienne, Roy, Sobhan, Scarpaci, Renee, Hwang, Hyeondo Luke, Henderson, J. Michael, Cao, Kathleen D., Bu, Wei, Lin, Binhua, Tietjen, Gregory T., Steck, Theodore L., Adams, Erin J., Lee, Ka Yee C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Hepatitis A Virus Cellular Receptor 1 Membrane Proteins Membranes Mice Mucins Phosphatidylserines
Online-Zugang:	Volltext
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