A Systematic Review and Meta-Analysis of High-Frequency Prescription of Zhigancao Decoction Combined with Conventional Western Medicine in the Treatment of Chronic Heart Failure
Background. Chronic heart failure is the main critical illness and cause of death in the later stages of cardiovascular disease, and it is one of the two major challenges in the field of cardiovascular research. The clinical application of traditional Chinese medicine in the prevention and treatment...
Gespeichert in:
| Veröffentlicht in: | Evidence-based complementary and alternative medicine 2021, Vol.2021, p.7140044-17 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 17 |
|---|---|
| container_issue | |
| container_start_page | 7140044 |
| container_title | Evidence-based complementary and alternative medicine |
| container_volume | 2021 |
| creator | Wu, Qianyan Zhang, Qingyuan Li, Yong Yu, Letian Zhang, Ying Ao, Meiying |
| description | Background. Chronic heart failure is the main critical illness and cause of death in the later stages of cardiovascular disease, and it is one of the two major challenges in the field of cardiovascular research. The clinical application of traditional Chinese medicine in the prevention and treatment of chronic heart failure has been relatively common in China, and the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine” has been published in China. Combining the literature in this field, the authors found that Zhigancao Decoction has been used in the treatment of chronic heart failure with more clinical research reports and higher frequency (this article refers to it as a high-frequency prescription for short). However, Zhigancao Decoction was not included in the recommended prescriptions in the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine,” and there was no relevant systematic review and meta-analysis. For this reason, this article has carried out two parts of work, including systematically organizing the literature in this research field and carrying out systematic review and meta-analysis. This can provide stronger evidence support for Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure and provide a new option for the improvement and update of the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine.” Methods. This article used the bibliometric method to investigate the research articles on the treatment of chronic heart failure with integrated traditional Chinese and Western medicine and analyzed the high-frequency prescriptions which are used and reported frequently. In addition, we also used manual and computer-aided search methods, the search scope includes CNKI, WANFANG, VIP, SinoMed, Web of Science, PubMed, and Cochrane Library, and the search content is the clinical randomized control of Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure trials (RCTs). The search period is from the establishment of the database to January 29, 2021. The literature was managed and screened by EndNote software; the quality of the included literature was evaluated according to the modified Jadad scale, and the risk bias |
| doi_str_mv | 10.1155/2021/7140044 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8595005</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2600066142</sourcerecordid><originalsourceid>FETCH-LOGICAL-c448t-e60dd2eaaab33d30891e56c49d811f5c1b33c7157f3f369b60d6a70360b08ee63</originalsourceid><addsrcrecordid>eNp9ksGO0zAQhiMEYpeFG2dkiQsShLUTO3YuK1WFUqRFIFgE4mK5zqTxKrGL7bTqY_GGOLRUwIGT7ZlP__wznix7TPBLQhi7LHBBLjmhGFN6JzsnnJKcFkLcPd3517PsQQi3GBc15_x-dlZSXjMu-Hn2Y4Y-7UOEQUWj0UfYGtghZRv0DqLKZ1b1-2ACci1amnWXLzx8H8HqPfrgIWhvNtE4O6W_dWatrFYOvQLt9K_w3A0rY6FBOxO79LJbsFNC9egLpKLepjKN0YlBxqLYAbrxoOKQsElz3nlnk60lKB_RQpl-9PAwu9eqPsCj43mRfV68vpkv8-v3b97OZ9e5plTEHCrcNAUopVZl2ZRY1ARYpWndCEJapkkKa04Yb8u2rOpVwivFcVnhFRYAVXmRXR10N-NqgEYnT171cuPNoPxeOmXk3xlrOrl2WylYzTBmSeDZUcC7NLQQ5WCChr5XFtwYZMHqmogCiwl9-g9660af5pSoCmNcVYQWiXpxoLR3IXhoT2YIltMuyGkX5HEXEv7kzwZO8O_PT8DzA9AZ26id-b_cT8hgvwM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2600066142</pqid></control><display><type>article</type><title>A Systematic Review and Meta-Analysis of High-Frequency Prescription of Zhigancao Decoction Combined with Conventional Western Medicine in the Treatment of Chronic Heart Failure</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>Wiley Online Library (Open Access Collection)</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Wu, Qianyan ; Zhang, Qingyuan ; Li, Yong ; Yu, Letian ; Zhang, Ying ; Ao, Meiying</creator><contributor>Shi, San Jun ; San Jun Shi</contributor><creatorcontrib>Wu, Qianyan ; Zhang, Qingyuan ; Li, Yong ; Yu, Letian ; Zhang, Ying ; Ao, Meiying ; Shi, San Jun ; San Jun Shi</creatorcontrib><description>Background. Chronic heart failure is the main critical illness and cause of death in the later stages of cardiovascular disease, and it is one of the two major challenges in the field of cardiovascular research. The clinical application of traditional Chinese medicine in the prevention and treatment of chronic heart failure has been relatively common in China, and the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine” has been published in China. Combining the literature in this field, the authors found that Zhigancao Decoction has been used in the treatment of chronic heart failure with more clinical research reports and higher frequency (this article refers to it as a high-frequency prescription for short). However, Zhigancao Decoction was not included in the recommended prescriptions in the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine,” and there was no relevant systematic review and meta-analysis. For this reason, this article has carried out two parts of work, including systematically organizing the literature in this research field and carrying out systematic review and meta-analysis. This can provide stronger evidence support for Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure and provide a new option for the improvement and update of the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine.” Methods. This article used the bibliometric method to investigate the research articles on the treatment of chronic heart failure with integrated traditional Chinese and Western medicine and analyzed the high-frequency prescriptions which are used and reported frequently. In addition, we also used manual and computer-aided search methods, the search scope includes CNKI, WANFANG, VIP, SinoMed, Web of Science, PubMed, and Cochrane Library, and the search content is the clinical randomized control of Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure trials (RCTs). The search period is from the establishment of the database to January 29, 2021. The literature was managed and screened by EndNote software; the quality of the included literature was evaluated according to the modified Jadad scale, and the risk bias was assessed using the Cochrane tool; the results of the included studies were analyzed using the Review Manager 5.3 software; the sources of heterogeneity between the studies were analyzed using Stata16.0 software for sensitivity analysis. Results. According to the bibliometric analysis, the maximum number of research reports is 553, which are arranged in descending order of 21 prescriptions, including Zhenwu Decoction, Zhigancao, and powder of five drugs containing poria. The second most frequently used prescription is Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure, but its systematic review and meta-analysis still need further research. A total of 17 clinical randomized controlled trials of Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure were included in the search, with a total of 1752 subjects. Meta-analysis results show that Zhigancao combined with conventional Western medicine is more effective than conventional Western medicine in the treatment of chronic heart failure. The advantages are the following 5 outcome indicators: total clinical effective rate, left ventricular ejection fraction, left ventricular end-diastolic diameter, B-type natriuretic peptide, and 6-minute walk test. Conclusions. There are many prescriptions combined with Western medicine to treat chronic heart failure, among which Zhigancao Decoction is the second most frequently used prescription. There are many original studies on Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure. The quality of the evaluation research shows that the overall standard is scientific, and a few experimental designs are slightly irregular. Meta-analysis shows that Zhigancao Decoction combined with conventional Western medicine has better therapeutic effects and safety than conventional Western medicine. This shows the characteristics and advantages of integrated Chinese and Western medicine in the treatment of cardiovascular diseases and is worth recommending.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2021/7140044</identifier><identifier>PMID: 34795787</identifier><language>eng</language><publisher>United States: Hindawi</publisher><subject>Asthma ; Bibliometrics ; Brain natriuretic peptide ; Cardiovascular diseases ; Chinese medicine ; Clinical trials ; Computer programs ; Congestive heart failure ; Diagnosis ; Disease ; Diuretics ; Edema ; Full text databases ; Heart failure ; Medical diagnosis ; Meta-analysis ; Prescriptions ; Review ; Reviews ; Sensitivity analysis ; Software ; Statistical analysis ; Systematic review ; Traditional Chinese medicine ; Vasoactive intestinal peptide ; Ventricle</subject><ispartof>Evidence-based complementary and alternative medicine, 2021, Vol.2021, p.7140044-17</ispartof><rights>Copyright © 2021 Qianyan Wu et al.</rights><rights>Copyright © 2021 Qianyan Wu et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2021 Qianyan Wu et al. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c448t-e60dd2eaaab33d30891e56c49d811f5c1b33c7157f3f369b60d6a70360b08ee63</citedby><cites>FETCH-LOGICAL-c448t-e60dd2eaaab33d30891e56c49d811f5c1b33c7157f3f369b60d6a70360b08ee63</cites><orcidid>0000-0001-8017-0277 ; 0000-0003-4542-423X ; 0000-0003-2344-0992 ; 0000-0003-4502-1772 ; 0000-0001-7770-7600 ; 0000-0003-3688-8411</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595005/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595005/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,4024,27923,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34795787$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Shi, San Jun</contributor><contributor>San Jun Shi</contributor><creatorcontrib>Wu, Qianyan</creatorcontrib><creatorcontrib>Zhang, Qingyuan</creatorcontrib><creatorcontrib>Li, Yong</creatorcontrib><creatorcontrib>Yu, Letian</creatorcontrib><creatorcontrib>Zhang, Ying</creatorcontrib><creatorcontrib>Ao, Meiying</creatorcontrib><title>A Systematic Review and Meta-Analysis of High-Frequency Prescription of Zhigancao Decoction Combined with Conventional Western Medicine in the Treatment of Chronic Heart Failure</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>Background. Chronic heart failure is the main critical illness and cause of death in the later stages of cardiovascular disease, and it is one of the two major challenges in the field of cardiovascular research. The clinical application of traditional Chinese medicine in the prevention and treatment of chronic heart failure has been relatively common in China, and the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine” has been published in China. Combining the literature in this field, the authors found that Zhigancao Decoction has been used in the treatment of chronic heart failure with more clinical research reports and higher frequency (this article refers to it as a high-frequency prescription for short). However, Zhigancao Decoction was not included in the recommended prescriptions in the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine,” and there was no relevant systematic review and meta-analysis. For this reason, this article has carried out two parts of work, including systematically organizing the literature in this research field and carrying out systematic review and meta-analysis. This can provide stronger evidence support for Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure and provide a new option for the improvement and update of the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine.” Methods. This article used the bibliometric method to investigate the research articles on the treatment of chronic heart failure with integrated traditional Chinese and Western medicine and analyzed the high-frequency prescriptions which are used and reported frequently. In addition, we also used manual and computer-aided search methods, the search scope includes CNKI, WANFANG, VIP, SinoMed, Web of Science, PubMed, and Cochrane Library, and the search content is the clinical randomized control of Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure trials (RCTs). The search period is from the establishment of the database to January 29, 2021. The literature was managed and screened by EndNote software; the quality of the included literature was evaluated according to the modified Jadad scale, and the risk bias was assessed using the Cochrane tool; the results of the included studies were analyzed using the Review Manager 5.3 software; the sources of heterogeneity between the studies were analyzed using Stata16.0 software for sensitivity analysis. Results. According to the bibliometric analysis, the maximum number of research reports is 553, which are arranged in descending order of 21 prescriptions, including Zhenwu Decoction, Zhigancao, and powder of five drugs containing poria. The second most frequently used prescription is Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure, but its systematic review and meta-analysis still need further research. A total of 17 clinical randomized controlled trials of Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure were included in the search, with a total of 1752 subjects. Meta-analysis results show that Zhigancao combined with conventional Western medicine is more effective than conventional Western medicine in the treatment of chronic heart failure. The advantages are the following 5 outcome indicators: total clinical effective rate, left ventricular ejection fraction, left ventricular end-diastolic diameter, B-type natriuretic peptide, and 6-minute walk test. Conclusions. There are many prescriptions combined with Western medicine to treat chronic heart failure, among which Zhigancao Decoction is the second most frequently used prescription. There are many original studies on Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure. The quality of the evaluation research shows that the overall standard is scientific, and a few experimental designs are slightly irregular. Meta-analysis shows that Zhigancao Decoction combined with conventional Western medicine has better therapeutic effects and safety than conventional Western medicine. This shows the characteristics and advantages of integrated Chinese and Western medicine in the treatment of cardiovascular diseases and is worth recommending.</description><subject>Asthma</subject><subject>Bibliometrics</subject><subject>Brain natriuretic peptide</subject><subject>Cardiovascular diseases</subject><subject>Chinese medicine</subject><subject>Clinical trials</subject><subject>Computer programs</subject><subject>Congestive heart failure</subject><subject>Diagnosis</subject><subject>Disease</subject><subject>Diuretics</subject><subject>Edema</subject><subject>Full text databases</subject><subject>Heart failure</subject><subject>Medical diagnosis</subject><subject>Meta-analysis</subject><subject>Prescriptions</subject><subject>Review</subject><subject>Reviews</subject><subject>Sensitivity analysis</subject><subject>Software</subject><subject>Statistical analysis</subject><subject>Systematic review</subject><subject>Traditional Chinese medicine</subject><subject>Vasoactive intestinal peptide</subject><subject>Ventricle</subject><issn>1741-427X</issn><issn>1741-4288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9ksGO0zAQhiMEYpeFG2dkiQsShLUTO3YuK1WFUqRFIFgE4mK5zqTxKrGL7bTqY_GGOLRUwIGT7ZlP__wznix7TPBLQhi7LHBBLjmhGFN6JzsnnJKcFkLcPd3517PsQQi3GBc15_x-dlZSXjMu-Hn2Y4Y-7UOEQUWj0UfYGtghZRv0DqLKZ1b1-2ACci1amnWXLzx8H8HqPfrgIWhvNtE4O6W_dWatrFYOvQLt9K_w3A0rY6FBOxO79LJbsFNC9egLpKLepjKN0YlBxqLYAbrxoOKQsElz3nlnk60lKB_RQpl-9PAwu9eqPsCj43mRfV68vpkv8-v3b97OZ9e5plTEHCrcNAUopVZl2ZRY1ARYpWndCEJapkkKa04Yb8u2rOpVwivFcVnhFRYAVXmRXR10N-NqgEYnT171cuPNoPxeOmXk3xlrOrl2WylYzTBmSeDZUcC7NLQQ5WCChr5XFtwYZMHqmogCiwl9-g9660af5pSoCmNcVYQWiXpxoLR3IXhoT2YIltMuyGkX5HEXEv7kzwZO8O_PT8DzA9AZ26id-b_cT8hgvwM</recordid><startdate>2021</startdate><enddate>2021</enddate><creator>Wu, Qianyan</creator><creator>Zhang, Qingyuan</creator><creator>Li, Yong</creator><creator>Yu, Letian</creator><creator>Zhang, Ying</creator><creator>Ao, Meiying</creator><general>Hindawi</general><general>Hindawi Limited</general><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8017-0277</orcidid><orcidid>https://orcid.org/0000-0003-4542-423X</orcidid><orcidid>https://orcid.org/0000-0003-2344-0992</orcidid><orcidid>https://orcid.org/0000-0003-4502-1772</orcidid><orcidid>https://orcid.org/0000-0001-7770-7600</orcidid><orcidid>https://orcid.org/0000-0003-3688-8411</orcidid></search><sort><creationdate>2021</creationdate><title>A Systematic Review and Meta-Analysis of High-Frequency Prescription of Zhigancao Decoction Combined with Conventional Western Medicine in the Treatment of Chronic Heart Failure</title><author>Wu, Qianyan ; Zhang, Qingyuan ; Li, Yong ; Yu, Letian ; Zhang, Ying ; Ao, Meiying</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c448t-e60dd2eaaab33d30891e56c49d811f5c1b33c7157f3f369b60d6a70360b08ee63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Asthma</topic><topic>Bibliometrics</topic><topic>Brain natriuretic peptide</topic><topic>Cardiovascular diseases</topic><topic>Chinese medicine</topic><topic>Clinical trials</topic><topic>Computer programs</topic><topic>Congestive heart failure</topic><topic>Diagnosis</topic><topic>Disease</topic><topic>Diuretics</topic><topic>Edema</topic><topic>Full text databases</topic><topic>Heart failure</topic><topic>Medical diagnosis</topic><topic>Meta-analysis</topic><topic>Prescriptions</topic><topic>Review</topic><topic>Reviews</topic><topic>Sensitivity analysis</topic><topic>Software</topic><topic>Statistical analysis</topic><topic>Systematic review</topic><topic>Traditional Chinese medicine</topic><topic>Vasoactive intestinal peptide</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wu, Qianyan</creatorcontrib><creatorcontrib>Zhang, Qingyuan</creatorcontrib><creatorcontrib>Li, Yong</creatorcontrib><creatorcontrib>Yu, Letian</creatorcontrib><creatorcontrib>Zhang, Ying</creatorcontrib><creatorcontrib>Ao, Meiying</creatorcontrib><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Evidence-based complementary and alternative medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wu, Qianyan</au><au>Zhang, Qingyuan</au><au>Li, Yong</au><au>Yu, Letian</au><au>Zhang, Ying</au><au>Ao, Meiying</au><au>Shi, San Jun</au><au>San Jun Shi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Systematic Review and Meta-Analysis of High-Frequency Prescription of Zhigancao Decoction Combined with Conventional Western Medicine in the Treatment of Chronic Heart Failure</atitle><jtitle>Evidence-based complementary and alternative medicine</jtitle><addtitle>Evid Based Complement Alternat Med</addtitle><date>2021</date><risdate>2021</risdate><volume>2021</volume><spage>7140044</spage><epage>17</epage><pages>7140044-17</pages><issn>1741-427X</issn><eissn>1741-4288</eissn><abstract>Background. Chronic heart failure is the main critical illness and cause of death in the later stages of cardiovascular disease, and it is one of the two major challenges in the field of cardiovascular research. The clinical application of traditional Chinese medicine in the prevention and treatment of chronic heart failure has been relatively common in China, and the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine” has been published in China. Combining the literature in this field, the authors found that Zhigancao Decoction has been used in the treatment of chronic heart failure with more clinical research reports and higher frequency (this article refers to it as a high-frequency prescription for short). However, Zhigancao Decoction was not included in the recommended prescriptions in the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine,” and there was no relevant systematic review and meta-analysis. For this reason, this article has carried out two parts of work, including systematically organizing the literature in this research field and carrying out systematic review and meta-analysis. This can provide stronger evidence support for Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure and provide a new option for the improvement and update of the “Expert Consensus on the Diagnosis and Treatment of Chronic Heart Failure with Integrated Traditional Chinese and Western Medicine.” Methods. This article used the bibliometric method to investigate the research articles on the treatment of chronic heart failure with integrated traditional Chinese and Western medicine and analyzed the high-frequency prescriptions which are used and reported frequently. In addition, we also used manual and computer-aided search methods, the search scope includes CNKI, WANFANG, VIP, SinoMed, Web of Science, PubMed, and Cochrane Library, and the search content is the clinical randomized control of Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure trials (RCTs). The search period is from the establishment of the database to January 29, 2021. The literature was managed and screened by EndNote software; the quality of the included literature was evaluated according to the modified Jadad scale, and the risk bias was assessed using the Cochrane tool; the results of the included studies were analyzed using the Review Manager 5.3 software; the sources of heterogeneity between the studies were analyzed using Stata16.0 software for sensitivity analysis. Results. According to the bibliometric analysis, the maximum number of research reports is 553, which are arranged in descending order of 21 prescriptions, including Zhenwu Decoction, Zhigancao, and powder of five drugs containing poria. The second most frequently used prescription is Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure, but its systematic review and meta-analysis still need further research. A total of 17 clinical randomized controlled trials of Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure were included in the search, with a total of 1752 subjects. Meta-analysis results show that Zhigancao combined with conventional Western medicine is more effective than conventional Western medicine in the treatment of chronic heart failure. The advantages are the following 5 outcome indicators: total clinical effective rate, left ventricular ejection fraction, left ventricular end-diastolic diameter, B-type natriuretic peptide, and 6-minute walk test. Conclusions. There are many prescriptions combined with Western medicine to treat chronic heart failure, among which Zhigancao Decoction is the second most frequently used prescription. There are many original studies on Zhigancao Decoction combined with conventional Western medicine in the treatment of chronic heart failure. The quality of the evaluation research shows that the overall standard is scientific, and a few experimental designs are slightly irregular. Meta-analysis shows that Zhigancao Decoction combined with conventional Western medicine has better therapeutic effects and safety than conventional Western medicine. This shows the characteristics and advantages of integrated Chinese and Western medicine in the treatment of cardiovascular diseases and is worth recommending.</abstract><cop>United States</cop><pub>Hindawi</pub><pmid>34795787</pmid><doi>10.1155/2021/7140044</doi><tpages>17</tpages><orcidid>https://orcid.org/0000-0001-8017-0277</orcidid><orcidid>https://orcid.org/0000-0003-4542-423X</orcidid><orcidid>https://orcid.org/0000-0003-2344-0992</orcidid><orcidid>https://orcid.org/0000-0003-4502-1772</orcidid><orcidid>https://orcid.org/0000-0001-7770-7600</orcidid><orcidid>https://orcid.org/0000-0003-3688-8411</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1741-427X |
| ispartof | Evidence-based complementary and alternative medicine, 2021, Vol.2021, p.7140044-17 |
| issn | 1741-427X 1741-4288 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8595005 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; Wiley Online Library (Open Access Collection); PubMed Central; Alma/SFX Local Collection |
| subjects | Asthma Bibliometrics Brain natriuretic peptide Cardiovascular diseases Chinese medicine Clinical trials Computer programs Congestive heart failure Diagnosis Disease Diuretics Edema Full text databases Heart failure Medical diagnosis Meta-analysis Prescriptions Review Reviews Sensitivity analysis Software Statistical analysis Systematic review Traditional Chinese medicine Vasoactive intestinal peptide Ventricle |
| title | A Systematic Review and Meta-Analysis of High-Frequency Prescription of Zhigancao Decoction Combined with Conventional Western Medicine in the Treatment of Chronic Heart Failure |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T07%3A03%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Systematic%20Review%20and%20Meta-Analysis%20of%20High-Frequency%20Prescription%20of%20Zhigancao%20Decoction%20Combined%20with%20Conventional%20Western%20Medicine%20in%20the%20Treatment%20of%20Chronic%20Heart%20Failure&rft.jtitle=Evidence-based%20complementary%20and%20alternative%20medicine&rft.au=Wu,%20Qianyan&rft.date=2021&rft.volume=2021&rft.spage=7140044&rft.epage=17&rft.pages=7140044-17&rft.issn=1741-427X&rft.eissn=1741-4288&rft_id=info:doi/10.1155/2021/7140044&rft_dat=%3Cproquest_pubme%3E2600066142%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2600066142&rft_id=info:pmid/34795787&rfr_iscdi=true |