Gastrin, via activation of PPARα, protects the kidney against hypertensive injury

Hypertensive nephropathy (HN) is a common cause of end-stage renal disease with renal fibrosis; chronic kidney disease is associated with elevated serum gastrin. However, the relationship between gastrin and renal fibrosis in HN is still unknown. We, now, report that mice with angiotensin II (Ang II...

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Veröffentlicht in:Clinical science (1979) 2021-01, Vol.135 (2), p.409-427
Hauptverfasser: Gu, Daqian, Fang, Dandong, Zhang, Mingming, Guo, Jingwen, Ren, Hongmei, Li, Xinyue, Zhang, Ziyue, Yang, Donghai, Zou, Xue, Liu, Yukai, Wang, Wei Eric, Wu, Gengze, Jose, Pedro A, Han, Yu, Zeng, Chunyu
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Sprache:eng
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