Upregulated Kynurenine Pathway Enzymes in Aortic Atherosclerotic Aneurysm: Macrophage Kynureninase Downregulates Inflammation

Aims: Inflammation and hypertension contribute to the progression of atherosclerotic aneurysm in the aorta. Vascular cell metabolism is regarded to modulate atherogenesis, but the metabolic alterations that occur in atherosclerotic aneurysm remain unknown. The present study aimed to identify metabol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Atherosclerosis and Thrombosis 2021/11/01, Vol.28(11), pp.1214-1240
Hauptverfasser:	Nishimura, Masanori, Yamashita, Atsushi, Matsuura, Yunosuke, Okutsu, Junichi, Fukahori, Aiko, Hirata, Tsuyoshi, Nishizawa, Tomohiro, Ishii, Hirohito, Maekawa, Kazunari, Nakamura, Eriko, Kitamura, Kazuo, Nakamura, Kunihide, Asada, Yujiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aneurysm Aortic Aneurysm - enzymology Aortic Aneurysm - pathology Atherosclerosis Atherosclerosis - enzymology Atherosclerosis - pathology Biomarkers - analysis Female Follow-Up Studies Gene Expression Profiling Humans Hydrolases - metabolism Inflammation - prevention & control Kynureninase Kynurenine pathway Macrophage Macrophages - enzymology Male Metabolome Original Prognosis Transcriptome Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!