DNA methylation changes in fibromyalgia suggest the role of the immune-inflammatory response and central sensitization

Fibromyalgia (FM) has been explained as a result of gene-environment interactions. The present study aims to verify DNA methylation differences in eleven candidate genome regions previously associated to FM, evaluating DNA methylation patterns as potential disease biomarkers. DNA methylation was ana...

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Veröffentlicht in:	Journal of clinical medicine 2021-10, Vol.10 (21), p.1-15
Hauptverfasser:	Gerra, Maria Carla, Carnevali, Davide, Ossola, Paolo, González-Villar, Alberto J., Pedersen, Inge Søkilde, Triñanes, Yolanda, Donnini, Claudia, Manfredini, Matteo, Arendt-Nielsen, Lars, Carrillo-de-la-Peña, Maria Teresa
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Blood Clinical medicine Depression Disease DNA methylation Epigenetics Fibromyalgia Gene expression Genetic testing Genomes Hypotheses Immune system Mental depression Pain Pain management Pathogenesis Rheumatology Science & Technology Sleep Sociodemographics Software
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