Association of Tumor Hydroxyindole O-Methyltransferase and Serum 5-Methoxytryptophan with Long-Term Survival of Hepatocellular Carcinoma

5-methoxytryptophan (5-MTP) is a recently discovered tryptophan (Trp) metabolite with anti-inflammatory and tumor-suppressing actions. Its synthesis is catalyzed by hydroxyindole O-methyltransferase (HIOMT). HIOMT levels were reported to be decreased in some patients with colorectal, pancreatic and...

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Veröffentlicht in:	Cancers 2021-10, Vol.13 (21), p.5311
Hauptverfasser:	Ko, Bor-Sheng, Liang, Shu-Man, Chang, Tzu-Ching, Wu, Jing-Yiing, Lee, Po-Hsun, Hsu, Yu-Juei, Kuo, Cheng-Chin, Liou, Jun-Yang, Wu, Kenneth K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biobanks Biomarkers Breast cancer Chromatography Fibroblasts Gene expression Hepatectomy Hepatocellular carcinoma Inflammation Liver Liver cancer Longitudinal studies Mass spectrometry Medical prognosis Melatonin Metabolism Metabolites Metastasis Methyltransferase Mortality mRNA Pancreatic cancer Patients Proteins Scientific imaging Serotonin Survival Tryptophan Tumors
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