Differential Expression Profiles and Functional Prediction of circRNAs in Necrotizing Enterocolitis

Circular RNAs (circRNAs), a novel type of noncoding RNAs, have been demonstrated to behave as microRNA (miRNA) sponges to exert their effects during pathological processes of diseases. However, the roles of circRNAs have not been explored in necrotizing enterocolitis (NEC). This study sought to iden...

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Veröffentlicht in:	BioMed research international 2021, Vol.2021, p.9862066-9, Article 9862066
Hauptverfasser:	Pan, Ya, Chen, Wenjuan, Yan, Xiangyun, Yu, Boshi, Yao, Shuwen, Chen, Xiaohui, Han, Shuping
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Animals, Newborn Binding sites Bioinformatics Biotechnology & Applied Microbiology Care and treatment Casualties Computational Biology - methods Diagnosis Encyclopedias Enterocolitis Enterocolitis, Necrotizing - genetics Enterocolitis, Necrotizing - metabolism Enterocolitis, Neonatal necrotizing Enterocolitis, Pseudomembranous Gastrointestinal diseases Gene expression Gene Expression - genetics Gene Expression Profiling - methods Gene Expression Regulation - genetics Gene Ontology Gene Regulatory Networks - genetics Genetic aspects Genomes Genomics Health aspects High-Throughput Nucleotide Sequencing - methods Ileum Ileum - metabolism Infants (Premature) Laboratory animals Life Sciences & Biomedicine Medicine, Research & Experimental Methods MicroRNA MicroRNAs MicroRNAs - genetics miRNA Necrosis Necrotizing enterocolitis Next-generation sequencing Pathogenesis Prospective Studies Rats Rats, Sprague-Dawley Research & Experimental Medicine Ribonucleic acid Risk factors RNA RNA sequencing RNA, Circular - analysis RNA, Circular - genetics Science & Technology Sepsis Small intestine Transcriptome - genetics
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