Variants Ala307Ala and Ser680Ser of 307 and 680 FSHr polymorphisms negatively influence on assisted reproductive techniques outcome and determine high probability of non-pregnancy in Caucasian patients

Purpose To determine the influence of different genotypes of Ala307Thr and Asn680Ser FSHr polymorphisms on controlled ovarian stimulation (COS) outcome and pregnancy. Methods This study collected blood and physiological and clinical parameters of 517 Caucasian patients (Statistical power ≥ 80%) that...

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Veröffentlicht in:	Journal of assisted reproduction and genetics 2021-10, Vol.38 (10), p.2769-2779
Hauptverfasser:	Monge-Ochoa, Belén, Montoro, Luis, Gil-Arribas, Elisa, Montoya, Julio, Ruiz-Pesini, Eduardo, López-Pérez, Manuel J., de Castro, Francisco, Díez-Sánchez, Carmen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Embryos Female Follicles Genetics Gynecology Human Genetics Humans Infertility, Female - genetics Infertility, Female - pathology Infertility, Female - therapy Medicine Medicine & Public Health Oocytes Ovulation Induction - statistics & numerical data Patients Polymorphism, Single Nucleotide Pregnancy Pregnancy Rate Receptors, FSH - genetics Reproduction Reproductive Medicine Reproductive Techniques, Assisted - adverse effects
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