Influenza immune escape under heterogeneous host immune histories

In a pattern called immune imprinting, individuals gain the strongest immune protection against the influenza strains encountered earliest in life. In many recent examples, differences in early infection history can explain birth year-associated differences in susceptibility (cohort effects). Suscep...

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Veröffentlicht in:	Trends in microbiology (Regular ed.) 2021-12, Vol.29 (12), p.1072-1082
Hauptverfasser:	Oidtman, Rachel J., Arevalo, Philip, Bi, Qifang, McGough, Lauren, Russo, Christopher Joel, Vera Cruz, Diana, Costa Vieira, Marcos, Gostic, Katelyn M.
Format:	Artikel
Sprache:	eng
Schlagworte:	antigenic evolution cohort effects Current sources Epidemics Humans immune escape Immune evasion Immune imprinting Imprinting Influenza Influenza, Human - epidemiology original antigenic sin
Online-Zugang:	Volltext
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