Functional Characterization of Ovine Dorsal Root Ganglion Neurons Reveal Peripheral Sensitization after Osteochondral Defect

Knee joint trauma can cause an osteochondral defect (OD), a risk factor for osteoarthritis (OA) and cause of debilitating pain in patients. Rodent OD models are less translatable because of their smaller joint size and open growth plate. This study proposes sheep as a translationally relevant model...

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Veröffentlicht in:	eNeuro 2021-09, Vol.8 (5), p.ENEURO.0237-21.2021
Hauptverfasser:	Chakrabarti, Sampurna, Ai, Minji, Wong, Katherine, Newell, Karin, Henson, Frances M D, Smith, Ewan St John
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Capsaicin Female Ganglia, Spinal Humans Neurons New Research Pain Sheep TRPV Cation Channels
Online-Zugang:	Volltext
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