Epigenetic Regulation of Interleukin-17-Related Genes and Their Potential Roles in Neutrophil Vascular Infiltration in Preeclampsia

DNA methylation is an epigenetic mechanism controlling gene expression, and reduced methylation is associated with increased gene expression. We hypothesized that IL-17 cytokines are regulated by DNA methylation, are elevated in the circulation of preeclamptic women, and stimulate vascular neutrophi...

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Veröffentlicht in:Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2022-01, Vol.29 (1), p.154-162
Hauptverfasser: Walsh, Scott W., Nugent, William H., Archer, Kellie J., Al Dulaimi, Marwah, Washington, Sonya L., Strauss, Jerome F.
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Sprache:eng
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