Toll receptors remodel epithelia by directing planar-polarized Src and PI3K activity

Toll-like receptors are essential for animal development and survival, with conserved roles in innate immunity, tissue patterning, and cell behavior. The mechanisms by which Toll receptors signal to the nucleus are well characterized, but how Toll receptors generate rapid, localized signals at the c...

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Veröffentlicht in:Developmental cell 2021-06, Vol.56 (11), p.1589-1602.e9
Hauptverfasser: Tamada, Masako, Shi, Jay, Bourdot, Kia S., Supriyatno, Sara, Palmquist, Karl H., Gutierrez-Ruiz, Omar L., Zallen, Jennifer A.
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Sprache:eng
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