Remote Ischaemic Conditioning in STEMI Patients in Sub-Saharan AFRICA: Rationale and Study Design for the RIC-AFRICA Trial

Purpose Despite evidence of myocardial infarct size reduction in animal studies, remote ischaemic conditioning (RIC) failed to improve clinical outcomes in the large CONDI-2/ERIC-PPCI trial. Potential reasons include that the predominantly low-risk study participants all received timely optimal repe...

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Veröffentlicht in:	Cardiovascular drugs and therapy 2023-04, Vol.37 (2), p.299-305
Hauptverfasser:	Lukhna, Kishal, Hausenloy, Derek J., Ali, Abdelbagi Sidahmed, Bajaber, Abdullah, Calver, Alistair, Mutyaba, Arthur, Mohamed, Awad Abdalla, Kiggundu, Brian, Chishala, Chishala, Variava, Ebrahim, Elmakki, Ehab Ali, Ogola, Elijah, Hamid, Eltayeb, Okello, Emmy, Gaafar, Isam, Mwazo, Keiran, Makotoko, Makoali, Naidoo, Mergan, Abdelhameed, Mohamed Elhadi, Badri, Motasim, van der Schyff, Nasief, Abozaid, Omaima, Xafis, Paul, Giesz, Sara, Gould, Trevor, Welgemoed, Waldo, Walker, Malcolm, Ntsekhe, Mpiko, Yellon, Derek M
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa South of the Sahara - epidemiology Blood pressure Cardiology Clinical outcomes Clinical trials Conditioning Congestive heart failure Double-Blind Method Heart failure Heart Failure - etiology Humans Ischemia Ischemia - etiology Ischemic Preconditioning, Myocardial - methods Low pressure Medicine Medicine & Public Health Myocardial infarction Optimization Pain Percutaneous Coronary Intervention - adverse effects Reperfusion Risk Size reduction ST Elevation Myocardial Infarction - diagnosis ST Elevation Myocardial Infarction - therapy Therapy Thrombolysis Treatment Outcome Trial Designs
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