Effects of Pregnancy and Isoniazid Preventive Therapy on Mycobacterium tuberculosis Interferon Gamma Response Assays in Women With HIV

Abstract Background Pregnancy is accompanied by immune suppression. We hypothesized that Mycobacterium tuberculosis-specific inflammatory responses used to identify latent tuberculosis infection (LTBI) lose positivity during pregnancy. We also hypothesized that isoniazid preventive therapy (IPT) may...

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Veröffentlicht in:Clinical infectious diseases 2021-11, Vol.73 (9), p.e3555-e3562
Hauptverfasser: Weinberg, Adriana, Aaron, Lisa, Montepiedra, Grace, Sterling, Timothy R, Browning, Renee, Mmbaga, Blandina, Vhembo, Tichaona, Naik, Shilpa, Kabugho, Enid, Masheto, Gaerolwe, Pahwa, Savita, Mathad, Jyoti S, LaCourse, Sylvia M, McCarthy, Katie, Bradford, Sarah, Theron, Gerhard, Costello, Diane, Zimmer, Bonnie, Pierre, Marie F, Gausi, Kamunkhwala, Denti, Paolo, Haas, David W, Gupta, Amita
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Sprache:eng
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