Coating of a Novel Antimicrobial Nanoparticle with a Macrophage Membrane for the Selective Entry into Infected Macrophages and Killing of Intracellular Staphylococci

Internalization of Staphylococcus aureus by macrophages can inactivate bacterial killing mechanisms, allowing intracellular residence and dissemination of infection. Concurrently, these staphylococci can evade antibiotics that are frequently unable to pass mammalian cell membranes. A binary, amphiph...

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Veröffentlicht in:	Advanced functional materials 2020-11, Vol.30 (48), p.n/a
Hauptverfasser:	Li, Yuanfeng, Liu, Yong, Ren, Yijin, Su, Linzhu, Li, Ang, An, Yingli, Rotello, Vincent, Zhang, Zhanzhan, Wang, Yin, Liu, Yang, Liu, Sidi, Liu, Jian, Laman, Jon D., Shi, Linqi, Mei, Henny C., Busscher, Henk J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Antiinfectives and antibacterials bacterial infections Blood circulation cell membrane encapsulation Cell membranes ciprofloxacin Encapsulation Lysozyme Macrophages Materials science Micelles Nanoparticles Receptors Scars Surface charge Toll‐like receptors triclosan
Online-Zugang:	Volltext
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