Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa
This study aimed to identify alcohol use patterns associated with viral non-suppression among women living with HIV (WLWH) and the extent to which adherence mediated these relationships. Baseline data on covariates, alcohol consumption, ART adherence, and viral load were collected from 608 WLWH on A...
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| Veröffentlicht in: | AIDS and behavior 2021-11, Vol.25 (11), p.3758-3769 |
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| creator | Myers, B. Lombard, C. Joska, J. A. Abdullah, F. Naledi, T. Lund, C. Petersen Williams, P. Stein, D. J. Sorsdahl, K. R. |
| description | This study aimed to identify alcohol use patterns associated with viral non-suppression among women living with HIV (WLWH) and the extent to which adherence mediated these relationships. Baseline data on covariates, alcohol consumption, ART adherence, and viral load were collected from 608 WLWH on ART living in the Western Cape, South Africa. We defined three consumption patterns: no/light drinking (drinking ≤ 1/week and ≤ 4 drinks/occasion), occasional heavy episodic drinking (HED) (drinking > 1 and ≤ 2/week and ≥ 5 drinks/occasion) and frequent HED (drinking ≥ 3 times/week and ≥ 5 drinks/occasion). In multivariable analyses, occasional HED (OR 3.07, 95% CI 1.78–5.30) and frequent HED (OR 7.11, 95% CI 4.24–11.92) were associated with suboptimal adherence. Frequent HED was associated with viral non-suppression (OR 2.08, 95% CI 1.30–3.28). Suboptimal adherence partially mediated the relationship between frequent HED and viral non-suppression. Findings suggest a direct relationship between frequency of HED and viral suppression. Given the mediating effects of adherence on this relationship, alcohol interventions should be tailored to frequency of HED while also addressing adherence. |
| doi_str_mv | 10.1007/s10461-021-03263-3 |
| format | Article |
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A. ; Abdullah, F. ; Naledi, T. ; Lund, C. ; Petersen Williams, P. ; Stein, D. J. ; Sorsdahl, K. R.</creator><creatorcontrib>Myers, B. ; Lombard, C. ; Joska, J. A. ; Abdullah, F. ; Naledi, T. ; Lund, C. ; Petersen Williams, P. ; Stein, D. J. ; Sorsdahl, K. R.</creatorcontrib><description>This study aimed to identify alcohol use patterns associated with viral non-suppression among women living with HIV (WLWH) and the extent to which adherence mediated these relationships. Baseline data on covariates, alcohol consumption, ART adherence, and viral load were collected from 608 WLWH on ART living in the Western Cape, South Africa. We defined three consumption patterns: no/light drinking (drinking ≤ 1/week and ≤ 4 drinks/occasion), occasional heavy episodic drinking (HED) (drinking > 1 and ≤ 2/week and ≥ 5 drinks/occasion) and frequent HED (drinking ≥ 3 times/week and ≥ 5 drinks/occasion). In multivariable analyses, occasional HED (OR 3.07, 95% CI 1.78–5.30) and frequent HED (OR 7.11, 95% CI 4.24–11.92) were associated with suboptimal adherence. Frequent HED was associated with viral non-suppression (OR 2.08, 95% CI 1.30–3.28). Suboptimal adherence partially mediated the relationship between frequent HED and viral non-suppression. Findings suggest a direct relationship between frequency of HED and viral suppression. Given the mediating effects of adherence on this relationship, alcohol interventions should be tailored to frequency of HED while also addressing adherence.</description><identifier>ISSN: 1090-7165</identifier><identifier>EISSN: 1573-3254</identifier><identifier>DOI: 10.1007/s10461-021-03263-3</identifier><identifier>PMID: 33876383</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Alcohol Drinking - epidemiology ; Alcohol use ; Alcoholic beverages ; Alcohols ; Antiretroviral therapy ; Beverages ; Consumption ; Consumption patterns ; Drinking ; Drinking behavior ; Ethanol ; Female ; Health Psychology ; HIV ; HIV Infections - drug therapy ; HIV Infections - epidemiology ; Human immunodeficiency virus ; Humans ; Infectious Diseases ; Medicine ; Medicine & Public Health ; Original Paper ; Public Health ; South Africa - epidemiology ; Viral Load ; Women ; Womens health</subject><ispartof>AIDS and behavior, 2021-11, Vol.25 (11), p.3758-3769</ispartof><rights>The Author(s) 2021</rights><rights>2021. The Author(s).</rights><rights>The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). 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We defined three consumption patterns: no/light drinking (drinking ≤ 1/week and ≤ 4 drinks/occasion), occasional heavy episodic drinking (HED) (drinking > 1 and ≤ 2/week and ≥ 5 drinks/occasion) and frequent HED (drinking ≥ 3 times/week and ≥ 5 drinks/occasion). In multivariable analyses, occasional HED (OR 3.07, 95% CI 1.78–5.30) and frequent HED (OR 7.11, 95% CI 4.24–11.92) were associated with suboptimal adherence. Frequent HED was associated with viral non-suppression (OR 2.08, 95% CI 1.30–3.28). Suboptimal adherence partially mediated the relationship between frequent HED and viral non-suppression. Findings suggest a direct relationship between frequency of HED and viral suppression. Given the mediating effects of adherence on this relationship, alcohol interventions should be tailored to frequency of HED while also addressing adherence.</description><subject>Alcohol Drinking - epidemiology</subject><subject>Alcohol use</subject><subject>Alcoholic beverages</subject><subject>Alcohols</subject><subject>Antiretroviral therapy</subject><subject>Beverages</subject><subject>Consumption</subject><subject>Consumption patterns</subject><subject>Drinking</subject><subject>Drinking behavior</subject><subject>Ethanol</subject><subject>Female</subject><subject>Health Psychology</subject><subject>HIV</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - epidemiology</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Paper</subject><subject>Public Health</subject><subject>South Africa - epidemiology</subject><subject>Viral Load</subject><subject>Women</subject><subject>Womens health</subject><issn>1090-7165</issn><issn>1573-3254</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>BHHNA</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kctu1TAQhi0Eohd4ARbIEhs2ATu-ZoOUVpRWOlKRSsvScpLxOa4S-2AnrXh7DKcXYNGF5RnPN79n9CP0hpIPlBD1MVPCJa1IXQ6rJavYM7RPhSpBLfjzEpOGVIpKsYcOcr4mhDRSNS_RHmNaSabZPlranGPv7exjyPgI5luAgL_aeYZUHqLD7djHTRzxZQZsw4CvfLIjXkU74Itlu02Qc-nF7RTDOs_4e5yKwMrf-LDGt37e4NOzK-wDvohLSVqXfG9foRfOjhle392H6PLk87fj02p1_uXsuF1VPVd8roRlTccdVTUAs0C15sw2Q-c6IpwlXPDaMaclpaLTWjOqeAcWur4bpK1hYIfo0053u3QTDD2EuQxvtslPNv000XrzbyX4jVnHG6OFJFKSIvD-TiDFHwvk2Uw-9zCONkBcsqkFFVJLyXlB3_2HXsclhbJeoRqilK65KlS9o_oUc07gHoahxPx21excNcVV88dVw0rT27_XeGi5t7EAbAfkUgprSI9_PyH7C5NRrsI</recordid><startdate>20211101</startdate><enddate>20211101</enddate><creator>Myers, B.</creator><creator>Lombard, C.</creator><creator>Joska, J. 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A.</au><au>Abdullah, F.</au><au>Naledi, T.</au><au>Lund, C.</au><au>Petersen Williams, P.</au><au>Stein, D. J.</au><au>Sorsdahl, K. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa</atitle><jtitle>AIDS and behavior</jtitle><stitle>AIDS Behav</stitle><addtitle>AIDS Behav</addtitle><date>2021-11-01</date><risdate>2021</risdate><volume>25</volume><issue>11</issue><spage>3758</spage><epage>3769</epage><pages>3758-3769</pages><issn>1090-7165</issn><eissn>1573-3254</eissn><abstract>This study aimed to identify alcohol use patterns associated with viral non-suppression among women living with HIV (WLWH) and the extent to which adherence mediated these relationships. Baseline data on covariates, alcohol consumption, ART adherence, and viral load were collected from 608 WLWH on ART living in the Western Cape, South Africa. We defined three consumption patterns: no/light drinking (drinking ≤ 1/week and ≤ 4 drinks/occasion), occasional heavy episodic drinking (HED) (drinking > 1 and ≤ 2/week and ≥ 5 drinks/occasion) and frequent HED (drinking ≥ 3 times/week and ≥ 5 drinks/occasion). In multivariable analyses, occasional HED (OR 3.07, 95% CI 1.78–5.30) and frequent HED (OR 7.11, 95% CI 4.24–11.92) were associated with suboptimal adherence. Frequent HED was associated with viral non-suppression (OR 2.08, 95% CI 1.30–3.28). Suboptimal adherence partially mediated the relationship between frequent HED and viral non-suppression. Findings suggest a direct relationship between frequency of HED and viral suppression. Given the mediating effects of adherence on this relationship, alcohol interventions should be tailored to frequency of HED while also addressing adherence.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>33876383</pmid><doi>10.1007/s10461-021-03263-3</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-0235-6716</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; SpringerNature Journals; Sociological Abstracts |
| subjects | Alcohol Drinking - epidemiology Alcohol use Alcoholic beverages Alcohols Antiretroviral therapy Beverages Consumption Consumption patterns Drinking Drinking behavior Ethanol Female Health Psychology HIV HIV Infections - drug therapy HIV Infections - epidemiology Human immunodeficiency virus Humans Infectious Diseases Medicine Medicine & Public Health Original Paper Public Health South Africa - epidemiology Viral Load Women Womens health |
| title | Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa |
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