Brain areas involved with obsessive-compulsive disorder present different DNA methylation modulation

Obsessive-compulsive disorder (OCD) is characterized by intrusive thoughts and repetitive actions, that presents the involvement of the cortico-striatal areas. The contribution of environmental risk factors to OCD development suggests that epigenetic mechanisms may contribute to its pathophysiology....

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Veröffentlicht in:	BMC genetics 2021-10, Vol.22 (1), p.45-45, Article 45
Hauptverfasser:	de Oliveira, Kátia Cristina, Camilo, Caroline, Gastaldi, Vinícius Daguano, Sant'Anna Feltrin, Arthur, Lisboa, Bianca Cristina Garcia, de Jesus Rodrigues de Paula, Vanessa, Moretto, Ariane Cristine, Lafer, Beny, Hoexter, Marcelo Queiroz, Miguel, Euripedes Constantino, Maschietto, Mariana, Brentani, Helena
Format:	Artikel
Sprache:	eng
Schlagworte:	Age differences Aged Analysis Antigens Apoptosis Biotechnology industry Brain Brain - metabolism Care and treatment Caudate Nucleus CpG islands CpG Islands - genetics Cytosine Deoxyribonucleic acid Diagnosis DNA DNA Methylation Environmental factors Epigenetic inheritance Epigenetics Female Gene expression Genes Genetic aspects Genetic transcription Guanine Gyrus Cinguli Health aspects Humans Immune response Immune System - metabolism Immunity - genetics Kinases Male Mental disorders Methylation Neostriatum Neuronal Plasticity - genetics Neurophysiology Neuroses Nucleus Accumbens Obsessive compulsive disorder Obsessive-Compulsive Disorder - genetics Phosphates Prefrontal Cortex Protein interaction Protein-protein interactions Proteins Putamen Risk factors Senescence Signal transduction Synapses Synaptic plasticity Transcription factors
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