Iron Metabolism and Idiopathic Pulmonary Arterial Hypertension: New Insights from Bioinformatic Analysis

Idiopathic pulmonary arterial hypertension (IPAH) is a rare vascular disease with a poor prognosis, and the mechanism of its development remains unclear. Further molecular pathology studies may contribute to a comprehensive understanding of IPAH and provide new insights into diagnostic markers and p...

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Veröffentlicht in:	BioMed research international 2021, Vol.2021 (1), p.5669412-5669412
Hauptverfasser:	Zou, Hua-Xi, Qiu, Bai-Quan, Lai, Song-Qing, Zhou, Xue-Liang, Gong, Cheng-Wu, Wang, Li-Jun, Yuan, Ming-Ming, He, An-Di, Liu, Ji-Chun, Huang, Huang
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Arteriosclerosis Atherosclerosis Biological activity Care and treatment China Cinnamaldehyde Computational biology Computational Biology - methods Databases, Genetic Datasets Diagnosis Drug development Familial Primary Pulmonary Hypertension - genetics Familial Primary Pulmonary Hypertension - metabolism Familial Primary Pulmonary Hypertension - physiopathology Ferroptosis Ferroptosis - physiology Fluid flow Gene expression Gene Expression - genetics Gene Expression Profiling - methods Genes Genetic aspects Homeostasis Humans Hypertension Identification and classification Iron Iron - metabolism Iron Deficiencies Iron deficiency Iron metabolism disorders Mechanical stimuli Medical prognosis Membrane Transport Proteins - genetics Membrane Transport Proteins - metabolism Metabolism MicroRNA MicroRNAs MicroRNAs - genetics Molecular modelling Mortality Nutrient deficiency Oxidative stress Oxidative Stress - genetics Oxidative Stress - physiology Physiological aspects Proteins Pulmonary arteries Pulmonary Artery - physiopathology Pulmonary hypertension Regulatory mechanisms (biology) Risk factors Shear stress Software Source studies Therapeutic applications Therapeutic targets Transcriptome - genetics Vascular diseases
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