In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease

Both the replication of protein aggregates and their spreading throughout the brain are implicated in the progression of Alzheimer’s disease (AD). However, the rates of these processes are unknown and the identity of the rate-determining process in humans has therefore remained elusive. By bringing...

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Veröffentlicht in:	Science advances 2021-10, Vol.7 (44), p.eabh1448-eabh1448
Hauptverfasser:	Meisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L, Sanchez, Justin S, Xu, Catherine K, Duff, Karen E, Johnson, Keith A, Rowe, James B, Hyman, Bradley T, Knowles, Tuomas P J, Klenerman, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysics Diseases and Disorders Neuroscience SciAdv r-articles
Online-Zugang:	Volltext
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