A Cell Cycle Progression-Derived Gene Signature to Predict Prognosis and Therapeutic Response in Hepatocellular Carcinoma

Objective. Dysregulation of cell cycle progression (CCP) is one of the hallmarks of cancer. Here, our study is aimed at developing a CCP-derived gene signature for predicting high-risk population of hepatocellular carcinoma (HCC). Methods. Our study retrospectively analyzed the transcriptome profili...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Disease markers 2021, Vol.2021, p.1986159-36
Hauptverfasser:	Hui, Yongfeng, Leng, Junzhi, Jin, Dong, Liu, Di, Wang, Genwang, Wang, Qi, Wang, Yanyang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Angiogenesis Apoptosis Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Calibration Cancer Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - therapy Cell cycle Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Chemical compounds Chemotherapy DNA repair Doxorubicin Female Fluvastatin Follow-Up Studies Gemcitabine Genes Genomes Genomics Health risks Hepatocellular carcinoma Histocompatibility antigen HLA Humans Hypoxia Immune checkpoint Immune system Infiltration Liver cancer Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver Neoplasms - therapy Male Medical prognosis Middle Aged Nomograms Patients Pharmacology Prognosis Regression analysis Regression models Retrospective Studies Risk analysis Risk assessment Risk factors Statistical analysis Subgroups Survival analysis Survival Rate Transcriptome Transcriptomes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!