High expression levels and the C3435T SNP of the ABCB1 gene are associated with lower survival in adult patients with acute myeloblastic leukemia in Mexico City

Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by different genetic alterations that cause changes in the normal mechanisms of differentiation, which are associated with chemoresistance. The ABCB1 gene is part of a family of ATP-binding cassette (ABC) transporte...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BMC medical genomics 2021-10, Vol.14 (1), p.251-251, Article 251
Hauptverfasser:	Olarte Carrillo, Irma, García Laguna, Anel Irais, De la Cruz Rosas, Adrián, Ramos Peñafiel, Christian Omar, Collazo Jaloma, Juan, Martínez Tovar, Adolfo
Format:	Artikel
Sprache:	eng
Schlagworte:	ABCB1: ATP binding cassette subfamily B member 1 Acute myeloid leukemia Adolescent Adult Aged Aged, 80 and over AML: acute myeloid leukemia ATP Binding Cassette Transporter, Subfamily B - genetics Bone marrow Cancer Chemoresistance Female Gene expression Genotypes Humans Leukemia Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - pathology Male Malignancy Medical prognosis Mexico Middle Aged Myeloblastic leukemia Myeloid leukemia Oncology, Experimental Patients Polymerase chain reaction Polymorphism Polymorphism, Single Nucleotide qRT-PCR: quantitative real-time polymerase chain reaction Real-Time Polymerase Chain Reaction Remission (Medicine) Single nucleotide polymorphisms Single-nucleotide polymorphism Survival Survival Rate Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!