Encephalopathy caused by Talisia esculenta intoxication in pregnant ewes and their newborn lambs
An outbreak of acute encephalopathy occurred in pregnant ewes and their newborn lambs associated with consumption of Talisia esculenta fruits and bark. Clinical signs in 5 adult pregnant ewes included drooling, bloat, tachypnea, depression, ataxia, body shaking, difficulty in rising, and recumbency....
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| Veröffentlicht in: | Journal of veterinary diagnostic investigation 2021-11, Vol.33 (6), p.1128-1132 |
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| container_title | Journal of veterinary diagnostic investigation |
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| creator | Almeida, Valdir M. Silva-Filho, Givaldo B. Bom, Hisadora A. S. C. Fonseca, Silvio M. C. Riet-Correa, Franklin Uzal, Francisco A. Woolard, Kevin D. Souza, Francisco A. L. Mendonça, Fábio S. |
| description | An outbreak of acute encephalopathy occurred in pregnant ewes and their newborn lambs associated with consumption of Talisia esculenta fruits and bark. Clinical signs in 5 adult pregnant ewes included drooling, bloat, tachypnea, depression, ataxia, body shaking, difficulty in rising, and recumbency. Three neonatal lambs born to some of those ewes had similar clinical signs. No significant gross abnormalities were observed on autopsy. Histologically, neuronal necrosis, axonal and dendritic swelling, and loss of Purkinje neurons were observed in the cerebellum. The observation of similar neurologic clinical signs and lesions in pregnant ewes and their neonatal lambs suggests that the toxic principle of T. esculenta crosses the placenta and reaches the fetus. |
| doi_str_mv | 10.1177/10406387211041098 |
| format | Article |
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The observation of similar neurologic clinical signs and lesions in pregnant ewes and their neonatal lambs suggests that the toxic principle of T. esculenta crosses the placenta and reaches the fetus.</description><identifier>ISSN: 1040-6387</identifier><identifier>EISSN: 1943-4936</identifier><identifier>DOI: 10.1177/10406387211041098</identifier><identifier>PMID: 34429005</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Animals ; Animals, Newborn ; Brain Diseases - chemically induced ; Brain Diseases - veterinary ; Brief Reports ; Female ; Pregnancy ; Sapindaceae - toxicity ; Sheep ; Sheep Diseases - chemically induced</subject><ispartof>Journal of veterinary diagnostic investigation, 2021-11, Vol.33 (6), p.1128-1132</ispartof><rights>2021 The Author(s)</rights><rights>2021 The Author(s) 2021 American Association of Veterinary Laboratory Diagnosticians</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c395t-60f265c1c963ce95d36c405bce631d9b3992959b4bcba9c63a621101c54f84983</citedby><cites>FETCH-LOGICAL-c395t-60f265c1c963ce95d36c405bce631d9b3992959b4bcba9c63a621101c54f84983</cites><orcidid>0000-0003-0681-1878 ; 0000-0002-8923-4473 ; 0000-0001-5641-0883 ; 0000-0001-5738-7785</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546472/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546472/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,21798,27901,27902,43597,43598,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34429005$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Almeida, Valdir M.</creatorcontrib><creatorcontrib>Silva-Filho, Givaldo B.</creatorcontrib><creatorcontrib>Bom, Hisadora A. 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L.</au><au>Mendonça, Fábio S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Encephalopathy caused by Talisia esculenta intoxication in pregnant ewes and their newborn lambs</atitle><jtitle>Journal of veterinary diagnostic investigation</jtitle><addtitle>J Vet Diagn Invest</addtitle><date>2021-11-01</date><risdate>2021</risdate><volume>33</volume><issue>6</issue><spage>1128</spage><epage>1132</epage><pages>1128-1132</pages><issn>1040-6387</issn><eissn>1943-4936</eissn><abstract>An outbreak of acute encephalopathy occurred in pregnant ewes and their newborn lambs associated with consumption of Talisia esculenta fruits and bark. Clinical signs in 5 adult pregnant ewes included drooling, bloat, tachypnea, depression, ataxia, body shaking, difficulty in rising, and recumbency. Three neonatal lambs born to some of those ewes had similar clinical signs. No significant gross abnormalities were observed on autopsy. 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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; SAGE Complete; PubMed Central; Alma/SFX Local Collection |
| subjects | Animals Animals, Newborn Brain Diseases - chemically induced Brain Diseases - veterinary Brief Reports Female Pregnancy Sapindaceae - toxicity Sheep Sheep Diseases - chemically induced |
| title | Encephalopathy caused by Talisia esculenta intoxication in pregnant ewes and their newborn lambs |
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