Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial cells injury of colitis through regulating pyroptosis by AMPK/Nrf2/NLRP3 inflammasome

Ulcerative colitis (UC) is a chronic inflammatory disease with increasing incidence and prevalence in many countries. The purpose of this study is to explore the function of Schisandrin B and its underlying molecular mechanisms in colitis. In this study, mice with colitis were induced by giving 2.0%...

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Veröffentlicht in:Aging (Albany, NY.) NY.), 2021-10, Vol.13 (19), p.23193-23209
Hauptverfasser: Zhang, Weiwei, Wang, Wusan, Shen, Chaozhuang, Wang, Xiaohu, Pu, Zhichen, Yin, Qin
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Sprache:eng
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