New Directions in Therapeutic Angiogenesis and Arteriogenesis in Peripheral Arterial Disease

The prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is typically caused by atherosclerotic obstructions in the large arteries to the leg(s). The most common clinical conseq...

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Veröffentlicht in:	Circulation research 2021-06, Vol.128 (12), p.1944-1957
Hauptverfasser:	Annex, Brian H., Cooke, John P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Stem Cells - transplantation Amputation, Surgical Angiogenesis Inducing Agents - therapeutic use Angiogenesis Modulating Agents - therapeutic use Animals Anticoagulants - therapeutic use Atherosclerosis - complications Endothelium, Vascular - metabolism Endovascular Procedures Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Intermittent Claudication - etiology Limb Salvage Lower Extremity - blood supply Lower Extremity - surgery Mice Microcirculation Myocardial Infarction - epidemiology Neovascularization, Physiologic - physiology Peripheral Arterial Disease - epidemiology Peripheral Arterial Disease - therapy Prevalence Proprotein Convertase 9 RNA, Untranslated - therapeutic use Stroke - epidemiology
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