The Abscopal Effect: A Review of Pre-Clinical and Clinical Advances

Radiotherapy has been used for more than a hundred years to cure or locally control tumors. Regression of tumors outside of the irradiated field was occasionally observed and is known as the abscopal effect. However, the occurrence of systemic anti-tumor effects was deemed too rare and unpredictable...

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Veröffentlicht in:	International journal of molecular sciences 2021-10, Vol.22 (20), p.11061
Hauptverfasser:	Janopaul-Naylor, James R, Shen, Yang, Qian, David C, Buchwald, Zachary S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - therapeutic use Antigens Apoptosis Cancer therapies CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism Clinical trials Colorectal cancer Combined Modality Therapy Energy Humans Immune checkpoint inhibitors Immune Checkpoint Inhibitors - therapeutic use Immunostimulation Immunotherapy Ipilimumab - therapeutic use Lymphocytes Metastasis Neoplasms - radiotherapy Neoplasms - therapy Patients Prostate cancer Radiation effects Radiation therapy Radiation, Ionizing Review Synergistic effect Tumors X-rays
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