Urethral Tissue Reconstruction Using the Acellular Dermal Matrix Patch Modified with Collagen-Binding VEGF in Beagle Urethral Injury Models

Objectives. Urethral tissue reconstruction for hypospadias is challenging for urologists. In this study, bovine acellular dermal matrix (ADM) patch loading with collagen-binding vascular endothelial growth factor (CBD-VEGF) was used to repair the urethral injury in beagles. Methods. The safety and e...

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Veröffentlicht in:	BioMed research international 2021, Vol.2021 (1), p.5502740-5502740
Hauptverfasser:	Wang, Yanni, Wang, Guannan, Hou, Xianglin, Zhao, Yannan, Chen, Bing, Dai, Jianwu, Sun, Ning
Format:	Artikel
Sprache:	eng
Schlagworte:	Acellular Dermis - metabolism Angiogenesis Angiography Animals Binding Biomedical materials Bladder Blood vessels Care and treatment Catheters Cattle Cell growth Collagen Collagen - metabolism Complications Disease Models, Animal Dogs Equipment and supplies Growth factors Health aspects Hypospadias Hypospadias - metabolism Hypospadias - pathology Hypospadias - surgery Implantation Injuries Male Medical imaging Methods Penis Pharmaceuticals Physiological aspects Quantitative analysis Reconstruction Reconstructive Surgical Procedures - methods Repair Scaffolds Skin & tissue grafts Software Surgery Surgery, Plastic Tissue engineering Tissue Scaffolds Tissues Urethra Urethra - chemistry Urethra - surgery Urethra - transplantation Urethral diseases Urinary organs Vascular endothelial growth factor Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism Wound healing Wound Healing - drug effects
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