Effects of Combined Varenicline With Nicotine Patch and of Extended Treatment Duration on Smoking Cessation: A Randomized Clinical Trial

IMPORTANCE: Smoking cessation medications are routinely used in health care. Research suggests that combining varenicline with the nicotine patch, extending the duration of varenicline treatment, or both, may increase cessation effectiveness. OBJECTIVE: To compare combinations of varenicline plus th...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2021-10, Vol.326 (15), p.1485-1493
Hauptverfasser:	Baker, Timothy B, Piper, Megan E, Smith, Stevens S, Bolt, Daniel M, Stein, James H, Fiore, Michael C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Carbon monoxide Carbon Monoxide - analysis Cigarette smoking Cigarettes Clinical trials Combined Modality Therapy - adverse effects Combined Modality Therapy - methods Confidence Intervals Double-Blind Method Drug addiction Female Health care Health services Humans Insomnia Male Middle Aged Nausea Nausea - epidemiology Nicotine Nicotinic Agonists - therapeutic use Odds Ratio Original Investigation Patients Placebos Placebos - therapeutic use Self Report Sleep disorders Sleep Initiation and Maintenance Disorders - epidemiology Smoking Smoking cessation Smoking Cessation - methods Temperance Therapy Time Factors Tobacco Use Cessation Devices Varenicline - therapeutic use Wisconsin
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