Replacement and Parallel Simplification of Nonhomologous Proteinases Maintain Venom Phenotypes in Rear-Fanged Snakes

Novel phenotypes are commonly associated with gene duplications and neofunctionalization, less documented are the cases of phenotypic maintenance through the recruitment of novel genes. Proteolysis is the primary toxic character of many snake venoms, and ADAM metalloproteinases, named snake venom me...

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Veröffentlicht in:	Molecular biology and evolution 2020-12, Vol.37 (12), p.3563-3575
Hauptverfasser:	Bayona-Serrano, Juan David, Viala, Vincent Louis, Rautsaw, Rhett M, Schramer, Tristan D, Barros-Carvalho, Gesiele A, Nishiyama, Milton Yutaka, Freitas-de-Sousa, Luciana A, Moura-da-Silva, Ana Maria, Parkinson, Christopher L, Grazziotin, Felipe Gobbi, Junqueira-de-Azevedo, Inácio L M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Discoveries Evolution, Molecular Matrix Metalloproteinases - genetics Matrix Metalloproteinases - metabolism Phenotype Proteolysis Snake Venoms - enzymology Snake Venoms - genetics Snakes - genetics Snakes - metabolism Transcriptome
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