Potent Anti-Inflammatory, Arylpyrazole-Based Glucocorticoid Receptor Agonists That Do Not Impair Insulin Secretion

Glucocorticoids (GCs) are widely used in medicine for their role in the treatment of autoimmune-mediated conditions, certain cancers, and organ transplantation. The transcriptional activities GCs elicit include transrepression, postulated to be responsible for the anti-inflammatory activity, and tra...

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Veröffentlicht in:	ACS medicinal chemistry letters 2021-10, Vol.12 (10), p.1568-1577
Hauptverfasser:	Kennedy, Brandon J, Lato, Ashley M, Fisch, Alexander R, Burke, Susan J, Kirkland, Justin K, Prevatte, Carson W, Dunlap, Lee E, Smith, Russell T, Vogiatzis, Konstantinos D, Collier, J. Jason, Campagna, Shawn R
Format:	Artikel
Sprache:	eng
Schlagworte:	Letter
Online-Zugang:	Volltext
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