Intrapulmonary pharmacokinetic profile of cefiderocol in mechanically ventilated patients with pneumonia

Abstract Objectives Lung penetration of cefiderocol, a novel siderophore cephalosporin approved for treatment of nosocomial pneumonia, has previously been evaluated in healthy subjects. This study assessed the intrapulmonary pharmacokinetic profile of cefiderocol at steady state in hospitalized, mec...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2021-10, Vol.76 (11), p.2902-2905
Hauptverfasser:	Katsube, Takayuki, Nicolau, David P, Rodvold, Keith A, Wunderink, Richard G, Echols, Roger, Matsunaga, Yuko, Menon, Anju, Portsmouth, Simon, Wajima, Toshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Cefiderocol Cephalosporins Humans Original Research Pneumonia - drug therapy Respiration, Artificial
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