Lead-Induced Motor Dysfunction Is Associated with Oxidative Stress, Proteome Modulation, and Neurodegeneration in Motor Cortex of Rats

Lead (Pb) is a toxic metal with great neurotoxic potential. The aim of this study was to investigate the effects of a long-term Pb intoxication on the global proteomic profile, oxidative biochemistry and neuronal density in motor cortex of adult rats, and the possible outcomes related to motor funct...

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Veröffentlicht in:Oxidative medicine and cellular longevity 2021, Vol.2021 (1), p.5595047-5595047
Hauptverfasser: Leão, Luana Ketlen Reis, Bittencourt, Leonardo Oliveira, Oliveira, Ana Carolina Alves, Nascimento, Priscila Cunha, Ferreira, Maria Karolina Martins, Miranda, Giza Hellen Nonato, Ferreira, Railson de Oliveira, Eiró-Quirino, Luciana, Puty, Bruna, Dionizio, Aline, Cartágenes, Sabrina Carvalho, Freire, Marco Aurelio M., Buzalaf, Marília Afonso Rabelo, Crespo-Lopez, Maria Elena, Maia, Cristiane Socorro Ferraz, Lima, Rafael Rodrigues
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Sprache:eng
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