Convalescent plasma associates with reduced mortality and improved clinical trajectory in patients hospitalized with COVID-19

BACKGROUNDEvidence supporting convalescent plasma (CP), one of the first investigational treatments for coronavirus disease 2019 (COVID-19), has been inconclusive, leading to conflicting recommendations. The primary objective was to perform a comparative effectiveness study of CP for all-cause, in-h...

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Veröffentlicht in:	The Journal of clinical investigation 2021-10, Vol.131 (20), p.1-13
Hauptverfasser:	Arnold Egloff, Shanna A, Junglen, Angela, Restivo, Joseph Sa, Wongskhaluang, Marjorie, Martin, Casey, Doshi, Pratik, Schlauch, Daniel, Fromell, Gregg, Sears, Lindsay E, Correll, Mick, Burris, 3rd, Howard A, LeMaistre, Charles F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Biomedical research Care and treatment Case-Control Studies Clinical Medicine Cohort Studies Coronaviruses COVID-19 COVID-19 - mortality COVID-19 - therapy Electronic medical records Evidence-Based Medicine Female Health care Hospital Mortality Hospital patients Humans Immunization, Passive Male Middle Aged Models, Statistical Mortality Multivariate Analysis Pandemics Patients Retrospective Studies Risk Factors SARS-CoV-2 Serology Time Factors Treatment Outcome United States - epidemiology Young Adult
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