Protocolized Postextubation Respiratory Support to Prevent Reintubation: A Randomized Clinical Trial

Respiratory support (noninvasive ventilation or high-flow nasal cannula) applied at the time extubation has been reported to reduce reintubation rates, but concerns regarding effectiveness have limited uptake into practice. The aim of the research is to determine if providing postextubation respirat...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2021-08, Vol.204 (3), p.294-302
Hauptverfasser: Casey, Jonathan D., Vaughan, Erin M., Lloyd, Bradley D., Billas, Peter A., Jackson, Karen E., Hall, Eric J., Toporek, Alexandra H., Buell, Kevin G., Brown, Ryan M., Richardson, Roger K., Rooks, J. Craig, Buie, Reagan B., Wang, Li, Lindsell, Christopher J., Ely, E. Wesley, Self, Wesley H., Bernard, Gordon R., Rice, Todd W., Semler, Matthew W.
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container_end_page 302
container_issue 3
container_start_page 294
container_title American journal of respiratory and critical care medicine
container_volume 204
creator Casey, Jonathan D.
Vaughan, Erin M.
Lloyd, Bradley D.
Billas, Peter A.
Jackson, Karen E.
Hall, Eric J.
Toporek, Alexandra H.
Buell, Kevin G.
Brown, Ryan M.
Richardson, Roger K.
Rooks, J. Craig
Buie, Reagan B.
Wang, Li
Lindsell, Christopher J.
Ely, E. Wesley
Self, Wesley H.
Bernard, Gordon R.
Rice, Todd W.
Semler, Matthew W.
description Respiratory support (noninvasive ventilation or high-flow nasal cannula) applied at the time extubation has been reported to reduce reintubation rates, but concerns regarding effectiveness have limited uptake into practice. The aim of the research is to determine if providing postextubation respiratory support to all patients undergoing extubation in a medical ICU would decrease the incidence of reintubation. The results of the study conclude that among a broad population of critically ill adults undergoing extubation from invasive mechanical ventilation at an academic medical center, protocolized postextubation respiratory support, primarily characterized by an increase in the use of high-flow nasal cannula, did not prevent reintubation compared with usual care.
doi_str_mv 10.1164/rccm.202009-3561OC
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source American Thoracic Society (ATS) Journals Online; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Airway management
Clinical trials
Critical care
Intubation
Original
Oxygen therapy
Respiration
Respiratory diseases
Respiratory distress syndrome
Ventilation
Ventilators
title Protocolized Postextubation Respiratory Support to Prevent Reintubation: A Randomized Clinical Trial
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