Critically ill COVID-19 patients exhibit hyperactive cytokine responses associated with effector exhausted senescent T cells in acute infection

COVID-19 can progress to severe pneumonia with respiratory failure and is aggravated by the deregulation of the immune system causing an excessive inflammation including the cytokine storm. We herein report that severe acutely infected patients have high levels of both type-1 and type-2 cytokines. O...

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Veröffentlicht in:	The Journal of infectious diseases 2021-08
Hauptverfasser:	Arcanjo, Angélica, Pinto, Kamila Guimarães, Logullo, Jorgete, Leite, Paulo Emílio Corrêa, Menezes, Camilla Cristie Barreto, Freire-de-Lima, Leonardo, Diniz-Lima, Israel, Decoté-Ricardo, Debora, Rodrigues-da-Silva, Rodrigo Nunes, Freire-de-Lima, Celio Geraldo, Filardy, Alessandra Almeida, Lima-Junior, Josué da Costa, Bertho, Alvaro Luiz, De Luca, Paula Mello, Granjeiro, José Mauro, Barroso, Shana Priscila Coutinho, Conceição-Silva, Fátima, Savino, Wilson, Morrot, Alexandre
Format:	Artikel
Sprache:	eng
Schlagworte:	Major
Online-Zugang:	Volltext
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