Impact of the Pd2Spm (Spermine) Complex on the Metabolism of Triple-Negative Breast Cancer Tumors of a Xenograft Mouse Model

The interest in palladium(II) compounds as potential new anticancer drugs has increased in recent years, due to their high toxicity and acquired resistance to platinum(II)-derived agents, namely cisplatin. In fact, palladium complexes with biogenic polyamines (e.g., spermine, Pd2Spm) have been known...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2021-10, Vol.22 (19), p.10775
Hauptverfasser:	Carneiro, Tatiana J., Araújo, Rita, Vojtek, Martin, Gonçalves-Monteiro, Salomé, de Carvalho, Ana L. M. Batista, Marques, Maria Paula M., Diniz, Carmen, Gil, Ana M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Biocompatibility Breast cancer Cancer therapies Chemotherapy Choline Cisplatin Cytotoxicity Discriminant analysis Drugs Guanidine In vivo methods and tests Lipophilic Lipophilicity Medical prognosis Metabolism Metabolites Metabolomics NMR Nuclear magnetic resonance Nucleotides Palladium Polyamines Principal components analysis Spermine Tumor cell lines Tumors Xenografts Xenotransplantation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!