Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders

Neurodegenerative disorders emerge from the failure of intricate cellular mechanisms, which ultimately lead to the loss of vulnerable neuronal populations. Research conducted across several laboratories has now provided compelling evidence that pathogenic proteins can also contribute to non-cell aut...

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Veröffentlicht in:Molecular psychiatry 2021-07, Vol.26 (7), p.2685-2706
Hauptverfasser: de Rus Jacquet, Aurélie, Denis, Hélèna L., Cicchetti, Francesca, Alpaugh, Melanie
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Sprache:eng
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