Mono-n-Butyl Phthalate Distributes to the Mouse Ovary and Liver and Alters the Expression of Phthalate-Metabolizing Enzymes in Both Tissues

Abstract Humans are exposed to phthalates daily via items such as personal care products and medications. Reproductive toxicity has been documented in mice exposed to di-n-butyl phthalate (DBP); however, quantitative evidence of its metabolite, mono-n-butyl phthalate (MBP), reaching the mouse ovary...

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Veröffentlicht in:	Toxicological sciences 2021-08, Vol.183 (1), p.117-127
Hauptverfasser:	Jauregui, Estela J, Lock, Jasmine, Rasmussen, Lindsay, Craig, Zelieann R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatography, Liquid Developmental and Reproductive Toxicology Dibutyl Phthalate - toxicity Female Liver Mice Ovary Phthalic Acids - toxicity Tandem Mass Spectrometry
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