The Latent Factor Structure Underlying Regional Brain Volume Change and Its Relation to Cognitive Change in Older Adults

Objective: Late-life changes in cognition and brain integrity are both highly multivariate, time-dependent processes that are essential for understanding cognitive aging and neurodegenerative disease outcomes. The present study seeks to identify a latent variable model capable of efficiently reducin...

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Veröffentlicht in:	Neuropsychology 2021-09, Vol.35 (6), p.643-655
Hauptverfasser:	Gavett, Brandon E., Fletcher, Evan, Widaman, Keith F., Tomaszewski Farias, Sarah, DeCarli, Charles, Mungas, Dan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atrophy - pathology Brain - diagnostic imaging Brain - pathology Brain Size Cognition Cognitive Aging Cognitive Dysfunction - diagnostic imaging Cognitive Dysfunction - pathology Cognitive Impairment Factor Analysis Factor Structure Female Gray Matter - diagnostic imaging Human Humans Magnetic Resonance Imaging Male Neurodegenerative Diseases - pathology Older Adulthood Statistical Variables
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