DeepDRIM: a deep neural network to reconstruct cell-type-specific gene regulatory network using single-cell RNA-seq data

Single-cell RNA sequencing has enabled to capture the gene activities at single-cell resolution, thus allowing reconstruction of cell-type-specific gene regulatory networks (GRNs). The available algorithms for reconstructing GRNs are commonly designed for bulk RNA-seq data, and few of them are appli...

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Veröffentlicht in:Briefings in bioinformatics 2021-11, Vol.22 (6)
Hauptverfasser: Chen, Jiaxing, Cheong, ChinWang, Lan, Liang, Zhou, Xin, Liu, Jiming, Lyu, Aiping, Cheung, William K, Zhang, Lu
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Sprache:eng
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