Can the Minimum Protamine Dose to Neutralize Heparin at the Completion of Cardiopulmonary Bypass be Significantly Lower than the Conventional Practice?

Systemic anticoagulation with heparin during cardiopulmonary bypass (CPB) should be neutralized by protamine administration to restore normal hemostasis. However, protamine has potentially serious side effects and excessive protamine can cause increased postoperative bleeding. Thus, our goal is to a...

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Veröffentlicht in:	The Journal of extra-corporeal technology 2021-09, Vol.53 (3), p.170-176
Hauptverfasser:	Lee, Min-Ho, Riley, William, Shann, Kenneth G
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiopulmonary Bypass Heparin Heparin Antagonists Humans Original Protamines Retrospective Studies
Online-Zugang:	Volltext
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