Photocatalytic Hydroaminoalkylation of Styrenes with Unprotected Primary Alkylamines

Catalytic, intermolecular hydroaminoalkylation (HAA) of styrenes provides a powerful disconnection for pharmacologically relevant γ-arylamines, but current methods cannot utilize unprotected primary alkylamines as feedstocks. Metal-catalyzed HAA protocols are also highly sensitive to α-substitution...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of the American Chemical Society 2021-10, Vol.143 (39), p.15936-15945
Hauptverfasser:	Askey, Hannah E, Grayson, James D, Tibbetts, Joshua D, Turner-Dore, Jacob C, Holmes, Jake M, Kociok-Kohn, Gabriele, Wrigley, Gail L, Cresswell, Alexander J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!